Fibrin Suspension Assay for Fibrinolytic Activity.

By A. E. D R AND D. Ku ui A GROWING INTEREST in fibrinolytic agents has given rise to a variety of methods for assessing the activity of such agents in vitro. The fibrin plate assay1 is a useful technic employing the natural substrate. Other methods,2 using formed fibrin clots, have also been devised, as well as technics employing other substrates such as casein. The purpose of this study was to examine the possibility of measuring fibrinolytic activity by the change in turbidity resulting from the dissolution of suspended particles of fibrin under the influence of fibrinolytic enzymes.